Submission Details
| 510(k) Number | K250821 FDA.gov |
| FDA Decision | Cleared SESE |
| Date Received | March 18, 2025 |
| Decision Date | December 12, 2025 |
| Days to Decision | 269 days |
| Submission Type | Traditional |
| Review Panel | Cardiovascular (CV) |
| Summary | Summary PDF |
K250821 is an FDA 510(k) clearance for the Horizon AF Plus System (Integrated A.L. One AF Plus OXYGENATOR and Horizon CVR) (US5300); A.L. One AF Plus OXYGENATOR (US5204); Horizon CVR (US5073), a Oxygenator, Cardiopulmonary Bypass (Class II — Special Controls, product code DTZ), submitted by Eurosets Srl (Medolla, IT). The FDA issued a Cleared decision on December 12, 2025, 269 days after receiving the submission on March 18, 2025. This device falls under the Cardiovascular review panel. Regulated under 21 CFR 870.4350.
| 510(k) Number | K250821 FDA.gov |
| FDA Decision | Cleared SESE |
| Date Received | March 18, 2025 |
| Decision Date | December 12, 2025 |
| Days to Decision | 269 days |
| Submission Type | Traditional |
| Review Panel | Cardiovascular (CV) |
| Summary | Summary PDF |
| Product Code | DTZ — Oxygenator, Cardiopulmonary Bypass |
| Device Class | Class II — Special Controls |
| CFR Regulation | 21 CFR 870.4350 |